STEPcare Trial

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Adaptive. Randomised. Novel: designed for humans.

You’re using Spinnaker! A user-friendly, bespoke application designed in New Zealand that helps researchers find answers. You can find out more about us and the people we work with through our blog posts and case studies.


They may have been five years in the making but the highly anticipated results for the TAME Trial arrived with a bang at this year’s Critical Care Review’s Meeting in Belfast.

Principal Investigator Glenn Eastwood and Ireland TAME Study Lead Alistair Nichol, took to the stage to announce that a strategy targeting mild hypercapnia for 24 hours did not improve neurologic outcomes at 6 months compared with targeted normocapnia.

Spiral has been on board with the TAME trial for over five years now and as one of the original trials in Spiral’s manifest we have been keenly awaiting these outcomes.

Read more on our blog


About the trial

After successful resuscitation, patients who survive a cardiac arrest often remain severely ill and require intensive care. Controlling depth of sedation, body temperature and mean arterial pressure are potential treatments that may prevent brain damage. The STEPCARE trial aims to study how to best apply these interventions.

About the software

This is Spinnaker, a user friendly, bespoke application that helps researchers find answers to important medical questions. The team behind the platform can adapt the software to match your study and we are especially interested in doing this for novel trials.

Spinnaker is a cloud based, integrated software/database solution for randomising patients using any design methodology including response adaptive methods; backed up by an electronic data capture application that is intuitive and particular. The application also includes management functions to alert relevant people about events (e.g. SAE), to manage drug inventory and to report on progress.

You can read more on the Spinnaker website at or contact Audrey on [email protected]

You can get to know us a little better through our blog and social media pages accessed via the logout screen of this trial.

Made with love in New Zealand.